T T Glant Selected Research

Aggrecans (Aggrecan)

1/2014	Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritis.
4/2011	Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis.
1/2010	Cartilage proteoglycan aggrecan epitopes induce proinflammatory autoreactive T-cell responses in rheumatoid arthritis and osteoarthritis.
11/2005	Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan.
7/2005	A longitudinal study on an autoimmune murine model of ankylosing spondylitis.
4/2004	Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis.
3/2003	TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage.
8/2002	Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice.
3/2001	Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease.
4/2000	Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.

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T T Glant Research Topics

Disease

17	Arthritis (Polyarthritis) 01/2014 - 04/2000
7	Rheumatoid Arthritis 01/2014 - 04/2000
4	Osteolysis 12/2001 - 09/2000
3	Autoimmune Diseases (Autoimmune Disease) 01/2014 - 03/2001
3	Inflammation (Inflammations) 04/2009 - 04/2000
3	Spondylitis 01/2008 - 03/2001
2	Osteoarthritis 01/2010 - 03/2003
1	Acne Vulgaris 12/2011
1	Colitis 04/2009
1	Sacroiliitis 01/2008
1	Ankylosing Spondylitis 01/2008
1	Spondylarthropathies 07/2005
1	Experimental Arthritis 04/2004
1	Bone Resorption 12/2001
1	Edema (Dropsy) 11/2001
1	Osteosarcoma (Osteogenic Sarcoma) 09/2000

Drug/Important Bio-Agent (IBA)

18	Proteoglycans (Proteoglycan)IBA 01/2014 - 04/2000
10	Aggrecans (Aggrecan)IBA 01/2014 - 04/2000
6	EpitopesIBA 01/2014 - 11/2005
5	CytokinesIBA 04/2011 - 04/2000
3	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2014 - 11/2005
3	Proteins (Proteins, Gene)FDA Link 02/2012 - 01/2010
2	AutoantigensIBA 01/2014 - 08/2002
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 02/2012 - 01/2008
2	ChemokinesIBA 01/2010 - 02/2001
2	AntigensIBA 08/2002 - 11/2001
1	DNA (Deoxyribonucleic Acid)IBA 06/2012
1	AntibodiesIBA 02/2012
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2011
1	Proline (L-Proline)FDA Link 12/2011
1	Peptides (Polypeptides)IBA 01/2010
1	Amino Acids FDA Link 01/2010
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 04/2009
1	NucleotidesIBA 04/2009
1	Collagen Type II (Type II Collagen)IBA 08/2002
1	Diphosphonates (Bisphosphonates)IBA 12/2001
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2001
1	Hyaluronic Acid (Hyaluronan)IBA 11/2001
1	EicosanoidsIBA 02/2001
1	Messenger RNA (mRNA)IBA 09/2000
1	ProcollagenIBA 09/2000
1	alpha 1 Chain Collagen Type IIBA 09/2000
1	Immunoglobulin G (IgG)IBA 04/2000

Therapy/Procedure

1	Intranasal Administration 08/2002
1	Intravenous Injections 11/2001